Dr. Javier García-Sancho
Instituto de Biología y Genética Molecular (IBGM), Universidad de Valladolid y CSIC, Valladolid, Spain
GAP, a new family of fluorescent protein probes for imaging calcium signals in intracellular organelles.
M.D. and Ph.D. Professor of Physiology in the Medical School, University of Valladolid (UVa), and Group Leader of the Cell Activation Unit of the Institute for Molecular Biology & Genetics (IBGM), a joint venture of the UVa and the Spanish Research Council (CSIC). Member of the Academia Europaea.
Our group’s main focus is on Cell Activation, especially on aspects related to the role of Ca2+ as a second messenger. During the last 25 years our group has studied Ca2+ signaling in relation to physiological functions and pathophysioly of blood cells, anterior pituitary, pancreatic islets, chromaffin cells and neurons. Recently, we have developed a new family of fluorescent Ca2+ probes based on aequorin, which are specially suitable for monitoring calcium signaling into intracellular organelles of living cells. During the last few years we have interested on the possibility of restoring lost function by Cell Therapy procedures and we have promoted translational research in this field through the Spanish Cell Therapy Network.
For further details see: http://www.ae-info.org/ae/User/Garc%C3%ADa-Sancho_Javier