Dr. Pablo Huertas
CABIMER/University of Seville
High resolution methods to analyze the repair of broken DNA.
Pablo Huertas studied Biology at the University of Seville, where he also obtained his PhD in Molecular and Cellular Biology in 2004 under the supervision of Andrés Aguilera. From 2004 until mid 2010 he worked as a postdoc in the laboratory of Stephen P. Jackson in The Gurdon Institute, University of Cambridge, United Kingdom. Since June 2010 he is a group leader at the Andalusian Center of Molecular Biology and Regenerative Medicine (CABIMER) and he is also part of the Department of Genetics of the University of Seville.
During his career, his research topics have evolved from the relationship of RNA metabolism with genomic instability in the budding yeast Saccharomyces cerevisiae, through the regulation of homologous recombination by the cell cycle in yeast and human cellular systems, to the repair of DNA double strand breaks in human cells. Nowadays, he is focused in understanding the complex regulatory network that control the choice between different DNA repair pathways, both at the cellular and organismal level, and the repercussions of altering such choice in terms of human disease.